Long-term Outcomes of Regressed or "Burnt Out" Primary Testicular Germ Cell Tumors.

ABSTRACT:

Objective

To review the presentation and long-term oncologic outcomes of patients with regressed ("burnt out") primary testicular germ cell tumors (GCT). Certain testicular GCT can present with complete regression of the primary tumor. It is not well established if this is associated with more aggressive disease or worse oncologic outcomes.

Methods

We queried our prospectively maintained testicular cancer clinical database at a tertiary cancer center and identified patients without prior chemotherapy who had regressed primary GCT at radical orchiectomy from 1990 to 2023. All specimens were reviewed by a genitourinary pathologist at diagnosis. Long-term clinical outcomes were reported by Kaplan-Meier method.

Results

Fifty-six patients met inclusion criteria; at diagnos

SUBMITTER: Baky FJ 

PROVIDER: S-EPMC11560521 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature