Investigating the metabolomic pathways in female reproductive endocrine disorders: a Mendelian randomization study.

ABSTRACT:

Introduction

Reproductive endocrine disorders (RED), including polycystic ovary syndrome (PCOS), endometriosis (EMs), and female infertility (FI), significantly affect women's health globally, with varying prevalence across different regions. These conditions can be addressed through medication, surgical interventions, and lifestyle modifications. However, the limited understanding of RED's etiology and the substantial economic burden of its treatment highlight the importance of investigating its pathogenesis. Metabolites play a critical role in metabolic processes and are potentially linked to the development of RED. Despite existing studies suggesting correlations between metabolites and RED, conclusive evidence remains scarce, primarily due to the observational nature of these s

SUBMITTER: Lu FF 

PROVIDER: S-EPMC11560792 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature