Phage biocontrol success of bacterial wilt depends on synergistic interactions with resident rhizosphere microbiota.

ABSTRACT: Phages can successfully be used in vitro and in planta to biocontrol the phytopathogenic Ralstonia solanacearum bacterium-the causal agent of bacterial wilt disease. However, phage biocontrol outcomes are still variable, and it is unclear what causes this. In this study, we assessed the efficiency of four phages in controlled in vitro and in planta experiments in all one- and two-phage combinations. We found that using phages in combination did not improve the phage biocontrol efficiency relative to single phage treatments, while certain phages and their combinations were more effective than the others. High intra-treatment variability in phage efficiency was observed across all phage treatments, which was associated with clear shifts in microbiome composition, a reduction in R. solanacear

SUBMITTER: Franco Ortega S 

PROVIDER: S-EPMC11561305 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature