The Therapeutic Use of Dental Mesenchymal Stem Cells in Human Clinical Trials.

ABSTRACT: Mesenchymal stem cells (MSCs), characterized by their undifferentiated and multipotent nature, can be derived from various sources, including bone marrow, adipose, and dental tissues. Among these, dental MSCs (DSCs) exhibit universal MSC characteristics and are attracting considerable attention for regenerating oral and craniofacial tissues. This review provides a contemporary overview of recently published clinical studies using DSCs for various orodental and maxillofacial regenerative applications, including bone, periodontal, and endodontic regeneration. It also explores the utilization of DSCs in treating systemic conditions, exemplified by their application in managing conditions such as COVID-19 and osteoarthritis. The available evidence underscores the potential of DSCs and their se

SUBMITTER: Ivanovski S 

PROVIDER: S-EPMC11562285 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature