Respiratory tract bacteria distribution and transmission patterns among individuals in close contact.

ABSTRACT:

Background

Respiratory disease outbreaks frequently occur in settings where individuals are in close contact, for example, schools and factories. However, the transmission patterns of oropharyngeal microbiota among healthy individuals living in clusters are unclear. Therefore, we aimed to investigate the respiratory tract bacteria distribution and transmission patterns among individuals in close contact.

Methods

A total of 36 freshmen from Peking University Medical School participated in the study. We collected pharyngeal swabs on the first day of enrollment, 15, 30, and 60 days after cohabitation. DNA was extracted from the swabs and subjected to high-throughput sequencing to profile the microbial composition. Statistical analyses were performed to assess diversity and sign

SUBMITTER: Zhao N 

PROVIDER: S-EPMC11562301 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature