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Dataset Information

Esophageal pressure as estimation of pleural pressure: a study in a model of eviscerated chest.


ABSTRACT:

Background

Transpulmonary pressure is the effective pressure across the lung parenchyma and has been proposed as a guide for mechanical ventilation. The pleural pressure is challenging to directly measure in clinical setting and esophageal manometry using esophageal balloon catheters was suggested for estimation. However, the accuracy of using esophageal pressure to estimate pleural pressure is debated due to variability in the mechanical properties of respiratory system, esophagus and esophageal catheter. Furthermore, while a vertical pleural pressure gradient exists across lung regions, esophageal pressure balloon provides a single value, representing, at most, the pressure surrounding the esophagus.

Methods

In a swine model with a preserved esophagus and a single homogeno

SUBMITTER: Florio G 

PROVIDER: S-EPMC11562330 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature