Transition to dolutegravir-based ART in 35 low- and middle-income countries: a global survey of HIV care clinics.

ABSTRACT:

Objective

We studied the transition to dolutegravir-containing antiretroviral therapy (ART) at HIV treatment clinics within the International epidemiology Databases to Evaluate AIDS (IeDEA).

Design

Site-level survey conducted in 2020-2021 among HIV clinics in low- and middle-income countries (LMICs).

Methods

We assessed the status of dolutegravir rollout and viral load and drug resistance testing practices for persons on ART switching to dolutegravir-based regimens. We used generalized estimating equations to assess associations between clinic rollout of both first- and second-line dolutegravir-based ART regimens (dual rollout) and site-level factors.

Results

Of 179 surveyed clinics, 175 (98%) participated; 137 (78%) from Africa, 30 (17%) from the Asia-Pacific,

SUBMITTER: Zaniewski E 

PROVIDER: S-EPMC11562491 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature