Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh.

ABSTRACT:

Background

Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).

Methods

To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.

Results

We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or

SUBMITTER: Carnegie L 

PROVIDER: S-EPMC11562509 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature