Lipoprotein-associated phospholipase A2 and its possible association with COPD development: a case-control study.

ABSTRACT:

Background

The association of lipoprotein-associated phospholipase A2 (Lp-PLA2) with various cardiovascular events has been well-established. However, the exploration of its potential involvement in Chronic obstructive pulmonary disease (COPD) is currently limited. Therefore, our study aims to examine the relationship between Lp-PLA2 and pulmonary conditions, including emphysema, obstructive ventilatory dysfunction as well as small airway dysfunction, to provide further evidence of a possible association with COPD development.

Methods

Using data from the Southwest Hospital Health Management Center, spanning January 2013 to July 2024, we analyze relationship of serum Lp-PLA2 levels with diffuse pulmonary emphysema and pulmonary functions. In univariate analysis, group differe

SUBMITTER: Yu H 

PROVIDER: S-EPMC11562620 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature