The association between age at menopause and bone health in Southwest China women: mediation effect of body mass index.

ABSTRACT:

Background

Previous studies have yielded inconsistent findings regarding the association between age at menopause and bone health, with limited exploration of potential mediating factors, particularly in the less-developed muti-ethnic regions of China. Our objective was to analyze the association between age at menopause and bone health among postmenopausal women in southwest China, while also examining the mediating effect of body mass index (BMI) and the moderating effect of years since menopause on this association.

Methods and results

The analysis included a total of 15,352 naturally postmenopausal women obtained from the baseline data of the China Multi-Ethnic Cohort (CMEC) Study. Multiple linear regression was used for multivariate analysis. Mediation analysis was cond

SUBMITTER: Chen J 

PROVIDER: S-EPMC11562631 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature