Education and metabolic syndrome: a Mendelian randomization study.

ABSTRACT:

Aims

The metabolic syndrome (MetS), a collection of conditions that heighten the risk of disease development and impose economic burdens on patients. However, the causal relationship between education and MetS was uncertain. In this study, the Mendelian randomization (MR) method was employed to elucidate the potential causal link between education and the MetS and its components.

Method

Single nucleotide polymorphisms (SNPs) associated with education, MetS, and its components were sourced from a public database, with the inverse variance-weighted (IVW) method utilized for analysis.

Results

Education demonstrated a significant negative correlation with the risk of MetS (OR = 0.55, 95% CI = 0.48-0.63, p = 2.18E-51), waist circumference(OR = 0.80, 95% CI = 0.76-0.

SUBMITTER: Liu D 

PROVIDER: S-EPMC11562850 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature