Trends in Positive Surgical Margins in cT3-T4 Oral Cavity Squamous Cell Carcinoma.

ABSTRACT:

Objective

Positive surgical margins in oral cavity squamous cell carcinoma are associated with cost escalation, treatment intensification, and greater risk of recurrence and mortality. The positive margin rate has been decreasing for cT1-T2 oral cavity cancer over the past 2 decades. We aim to evaluate positive margin rates in cT3-T4 oral cavity cancer over time, and determine factors associated with positive margins.

Study design

Retrospective analysis of a national database.

Setting

National Cancer Database 2004 to 2018.

Methods

All adult patients diagnosed between 2004 and 2018 who underwent primary curative intent surgery for previously untreated cT3-T4 oral cavity cancer with known margin status were included. Logistic univariable and multivariable regress

SUBMITTER: Prasad K 

PROVIDER: S-EPMC11563581 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature