Psychiatric predictors of quality of life in Parkinson's disease: A three-year longitudinal study.

ABSTRACT:

Introduction

Parkinson's disease (PD) is associated with worsened quality of life (QOL) over time. Few longitudinal studies exist investigating the relationship of psychiatric comorbidities with QOL in people with PD (PwP). We sought to determine specific psychiatric symptoms associated with decreasing QOL in PwP over time.

Methods

We recruited PwP without dementia from a movement disorders clinic at an academic medical center. Participants were evaluated annually with motor and neuropsychological assessments at each visit. QOL was measured using the Parkinson's Disease Questionnaire-39 (PDQ-39). We assessed psychiatric symptoms, including depression (Beck Depression Inventory II, BDI-II), anxiety (Beck Anxiety Index, BAI), and apathy (Apathy Scale). Psychosis and impulse co

SUBMITTER: Dalrymple WA 

PROVIDER: S-EPMC11563906 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature