The brain's structural connectivity and pre-reading abilities in young children with prenatal alcohol exposure.

ABSTRACT: Children with prenatal alcohol exposure (PAE) may develop a range of neurological and behavioral deficits, including reading and language disorders. Studying the brain's structural connectivity and its relationship to pre-reading/reading skills in young children with PAE can help understand the roots of reading deficits associated with PAE. 363 diffusion MRI scans from 135 children (114 scans from 53 children with PAE) were collected between ages 3-7 years. Children completed NEPSY-II Phonological Processing and Speeded Naming to assess pre-reading skills at each scan. Structural brain network properties were assessed in 16 regions from both hemispheres using graph theory. Linear mixed models were used to account for repeated measures within participants. Children with PAE had significantl

SUBMITTER: Ghasoub M 

PROVIDER: S-EPMC11564048 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature