Multimorbidity and risk of adverse outcomes in the Hertfordshire Cohort Study: does sex matter?

ABSTRACT:

Aims

We examined whether admission risk increases at a certain threshold of number of systems medicated or whether any increase confers greater admission risk in either sex in a community-dwelling cohort of older persons in Hertfordshire. This study uses a longitudinal retrospective study design.

Methods

Data from 2997 men and women (aged 59-73 at baseline) were analyzed. Participants were followed up from baseline (1998-2004) until December 2018 using Hospital Episode Statistics and mortality data, reporting clinical outcomes using ICD-10 coding. Number of systems medicated in relation to mortality (all-cause, cancer-related, cardiovascular-related) and admission (any, neurological, cardiovascular, and respiratory) were examined using Cox regression.

Results

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SUBMITTER: Westbury LD 

PROVIDER: S-EPMC11564394 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature