KSDKG: construction and application of knowledge graph for kidney stone disease based on biomedical literature and public databases.

ABSTRACT:

Purpose

Kidney stone disease (KSD) is a common urological disorder with an increasing incidence worldwide. The extensive knowledge about KSD is dispersed across multiple databases, challenging the visualization and representation of its hierarchy and connections. This paper aims at constructing a disease-specific knowledge graph for KSD to enhance the effective utilization of knowledge by medical professionals and promote clinical research and discovery.

Methods

Text parsing and semantic analysis were conducted on literature related to KSD from PubMed, with concept annotation based on biomedical ontology being utilized to generate semantic data in RDF format. Moreover, public databases were integrated to construct a large-scale knowledge graph for KSD. Additionally, case stu

SUBMITTER: Man J 

PROVIDER: S-EPMC11564440 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature