HPLC-MS/MS monitoring and health risk assessment of carbosulfan and its metabolites in date palm fruit (Phoenix dactylifera).

ABSTRACT: This study investigated residual levels of carbosulfan and its metabolites in date palm fruit in the UAE using HPLC-MS/MS and QuEChERS method. The method demonstrated excellent linearity (R² > 0.998), low LOD (0.001-0.04 μg/kg) and LOQ (0.003-0.1 μg/kg), and high recoveries (92-103%) with low RSD values (1-9%). The matrix effect was negligible (-16.43-17.09%), and uncertainty measurements did not exceed the 50% limit. Carbosulfan was present in all samples, exceeding its MRL in 46% of the samples. Carbofuran and 3-hydroxycarbofuran exceeded their MRL in 4.87% and 40% of the samples, respectively, while 3-ketocarbofuran levels were below the MRL. Dibutylamine was found in 82% of the samples, with an average concentration of 9.01 µg/kg. The health risk assessment for children and

SUBMITTER: Morsi R 

PROVIDER: S-EPMC11564510 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature