Characterization of Schiff base self-healing hydrogels by dynamic speckle pattern analysis.

ABSTRACT: Self-healing hydrogels are emerging materials capable of restoring functionality after damage, making them highly suitable for biomedical applications, such as tissue engineering, wound healing, and drug delivery. In this study, we synthesize and characterize a novel biodegradable, conductive, and self-healing hydrogel. The synthesis is based on a Schiff base formed between gelatin and hyaluronic acid, and the dynamic reversible Schiff base bond provides the self-healing property. To characterize and assess the self-healing behavior of the hydrogel, dynamic speckle pattern (DSP) analysis is introduced as a non-destructive, non-contact, and easy-to-implement method. Speckle patterns are formed upon scattering of laser light from a diffusive matter and includes a huge overall information abo

SUBMITTER: Sajjadi M 

PROVIDER: S-EPMC11564514 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature