Nomogram for predicting early recurrence of hepatocellular carcinoma with narrow resection margin.

ABSTRACT:

Purpose

Narrow resection margin hepatocellular carcinoma (NRM-HCC) has a high incidence of early recurrence. Our study was designed to identify prognostic factors in patients with NRM-HCC, establish and validate a nomogram model to predict early recurrence of NRM-HCC patients.

Methods

We retrospectively analyzed data from 2957 NRM-HCC patients who underwent radical hepatectomy at three medical centers between December 2009 and January 2015. Patients were randomly assigned to a training cohort (n = 2069) and a validation cohort (n = 888). Using univariate and multivariate COX regression to determine early relapse factors in NRM-HCC patients, and used these factors to construct a nomogram. The accuracy of the prediction was evaluated using the C-index, receiver operating chara

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11564854 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature