Development and validation of a prognostic nomogram for elderly-onset pancreatic neuroendocrine carcinoma: a prospective cohort study from the SEER database.

ABSTRACT:

Background

The incidence of elderly-onset pancreatic neuroendocrine carcinoma (PanNEC) is increasing. This study investigated independent risk factors affecting cancer-specific survival (CSS) and constructed a nomogram to predict CSS in patients with elderly-onset PanNEC.

Methods

PanNEC patients older than 50 years from the Surveillance, Epidemiology, and End Results database were retrospectively selected from 2010 to 2021 and were randomly divided into a training set and a validation set. Independent factors affecting CSS were selected by univariate and multivariate analyses. The nomogram was built using significant variables. The discrimination and calibration of the nomogram were evaluated by the area under the receiver operating characteristic curve (AUC), calibration cu

SUBMITTER: Liu H 

PROVIDER: S-EPMC11565105 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature