Midpregnancy Placental Growth Factor Screening and Early Preterm Birth.

ABSTRACT:

Importance

Early preterm birth (ie, at less than 34 weeks' gestation) confers a high risk for adverse health outcomes, yet no universal screening strategy exists, preventing targeted delivery of effective interventions.

Objective

To evaluate the ability of midpregnancy placental growth factor (PlGF) screening to identify pregnancies at highest risk for early preterm birth.

Design, setting, and participants

This prospective cohort study was conducted at an urban, tertiary care center from 2020 to 2023. Participants were unselected, pregnant people with singleton pregnancies, receiving universal-access prenatal care from obstetricians, family physicians, or midwives, who underwent a PlGF test at the time of routine gestational diabetes screening, typically at 24 to 28 w

SUBMITTER: Gladstone RA 

PROVIDER: S-EPMC11565265 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature