Comparative efficacy of doxycycline and its analogues with autologous blood patch pleurodesis for persistent air leak following secondary spontaneous pneumothorax in adults-a systematic review.

ABSTRACT:

Background

The presence of free air in the pleural space of lungs is termed pneumothorax and in individuals with underlying lung disease, it is known as secondary spontaneous pneumothorax. The incidence of spontaneous pneumothorax is 16 to 18 per lakh population. The most common causes for secondary spontaneous pneumothorax are chronic obstructive pulmonary disease (COPD), tuberculosis (TB), human immunodeficiency virus (HIV), cystic fibrosis of lung, and history of smoking. The clinical signs and symptoms include acute dyspnea, thoracic pain and cough. Persistent air leaks are frequently seen in secondary spontaneous pneumothorax. The incidence of persistent air leaks in post-surgical patients varies from 8% to 43%. The aim of the study is to compare the efficacy of doxycycline, t

SUBMITTER: Bhagat M 

PROVIDER: S-EPMC11565308 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature