Double-Bridging Increases the Stability of Zinc(II) Metal-Organic Cages.

ABSTRACT: A key feature of coordination cages is the dynamic nature of their coordinative bonds, which facilitates the synthesis of complex polyhedral structures and their post-assembly modification. However, this dynamic nature can limit cage stability. Increasing cage robustness is important for real-world use cases. Here we introduce a double-bridging strategy to increase cage stability, where designed pairs of bifunctional subcomponents combine to generate rectangular tetratopic ligands within pseudo-cubic Zn₈L₆ cages. These cages withstand transmetalation, the addition of competing ligands, and nucleophilic imines, under conditions where their single-bridged congeners decompose. Our approach not only increases the stability and robustness of the cages while maintaining the

SUBMITTER: Kurz H 

PROVIDER: S-EPMC11565643 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature