Error rates in <i>Q</i> _<i>ST</i> -<i>F</i> _<i>ST</i> comparisons depend on genetic architecture and estimation procedures.

ABSTRACT: Genetic and phenotypic variation among populations is one of the fundamental subjects of evolutionary genetics. One question that arises often in data on natural populations is whether differentiation among populations on a particular trait might be caused in part by natural selection. For the past several decades, researchers have used QST-FST approaches to compare the amount of trait differentiation among populations on one or more traits (measured by the statistic QST ) with differentiation on genome-wide genetic variants (measured by FST ). Theory says that under neutrality, FST and QST should be approximately equal in expectation, so QST values much larger than FST are consistent with local adaptation driving subpopulations' trait values apart, and QST values much smaller than FST are

SUBMITTER: Liu JJ 

PROVIDER: S-EPMC11565820 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature