Brain functional connectivity, but not neuroanatomy, captures the interrelationship between sex and gender in preadolescents.

ABSTRACT: Understanding sex differences in the adolescent brain is crucial, as these differences are linked to neurological and psychiatric conditions that vary between males and females. Predicting sex from adolescent brain data may offer valuable insights into how these variations shape neurodevelopment. Recently, attention has shifted toward exploring socially-identified gender, distinct from sex assigned at birth, recognizing its additional explanatory power. This study evaluates whether resting-state functional connectivity (rsFC) or cortical thickness more effectively predicts sex and sex/gender alignment (the congruence between sex and gender) and investigates their interrelationship in preadolescents. Using data from the Adolescent Brain Cognitive Development (ABCD) Study, we employed machin

SUBMITTER: Metoki A 

PROVIDER: S-EPMC11565917 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature