Pharmacogenotyping disproves genetic cause of drug-related problems in family history: a case report.

ABSTRACT:

Background

In clinical practice, family medication history is not routinely assessed as part of a patient's family health history (FHH). The information is self-reported and can depend on the individual's subjective perception. To illustrate how pharmacogenetic (PGx) testing results could be used to validate self-reported family medication history on drug-related problems (DRP), as well as to inform medication-related decisions, we herein present a case involving ten members of the same family.

Case presentation

Prior to a planned surgery, a preemptive PGx panel test was performed for a nine-year-old girl due to self-reported family medication history. The PGx panel test was also performed for her three siblings, parents, and grandparents. The focus was directed to the pater

SUBMITTER: Bollinger A 

PROVIDER: S-EPMC11566219 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature