Effect of choline alfoscerate in older adult patients with dementia: an observational study from the claims data of national health insurance.

ABSTRACT:

Background

Choline alfoscerate, a cholinergic precursor with limited evidence of efficacy in dementia management, has been used for various cognitive impairments in Korea. Partly due to its insurance coverage, this agent appears to incur significant expense for the insurance system. Thus, we aimed to describe choline alfoscerate prescription patterns and analyze their long-term effects in an older adult cohort with dementia.

Methods

This observational study used the National Health Insurance Service Senior Cohort Dataset. Choline alfoscerate -naïve patients who were diagnosed with dementia between 2003 and 2014 with at least 12 months of follow-up were selected. Time-dependent Cox regression was employed to estimate the association between drug exposure and the risk of treat

SUBMITTER: Duong KL 

PROVIDER: S-EPMC11566286 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature