The human plasma lipidome response to exertional heat tolerance testing.

ABSTRACT:

Background

The year of 2023 displayed the highest average global temperatures since it has been recorded-the duration and severity of extreme heat are projected to increase. Rising global temperatures represent a major public health threat, especially to occupations exposed to hot environments, such as construction and agricultural workers, and first responders. Despite efforts of the scientific community, there is still a need to characterize the pathophysiological processes leading to heat related illness and develop biomarkers that can predict its onset.

Methods

Liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based lipidomics analysis was performed on plasma from male and female subjects who underwent exertional heat tolerance testing (HTT), consisting of a 2-h

SUBMITTER: Estevao IL 

PROVIDER: S-EPMC11566608 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature