Missing outcome data in randomised clinical trials of psychological interventions: a review of published trial reports in major psychiatry journals.

ABSTRACT:

Background

Missing outcome data can pose a serious threat to the validity of randomised clinical trial results. We aimed to study the extent of missing outcome data in randomised clinical trials of psychological interventions.

Methods

We performed a retrospective study of randomised clinical trial reports of psychological interventions published in World Psychiatry, JAMA Psychiatry, Lancet Psychiatry, American Journal of Psychiatry, British Journal of Psychiatry, or Psychotherapy and Psychosomatics from 2017 to 2022. We assessed the proportion of missing outcome data, whether missing data patterns differed between types of outcomes, participants, intervention lengths, and psychological intervention types, how missing outcome data were handled in the statistical analyses, and

SUBMITTER: Juul S 

PROVIDER: S-EPMC11566980 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature