Long-chain polyunsaturated fatty acid-containing phosphatidylcholines predict survival rate in patients after heart failure.

ABSTRACT:

Background

Heart failure (HF) is becoming an increasingly prevalent issue, particularly among the elderly population. Lipids are closely associated with cardiovascular disease (CVD) pathology. Lipidomics as a comprehensive profiling tool is showing to be promising in the prediction of events and mortality due to CVD as well as identifying novel biomarkers.

Materials and methods

In this study, eicosanoids and lipid profiles were measured in order to predict survival in patients with de novo or acute decompensated HF. Our study included 50 patients (16 females, mean age 73 years and 34 males, mean age 71 years) with de novo or acute decompensated chronic HF with a median follow-up of 7 months. Lipids were semiquantified using targeted lipidomic liquid chromatography-mass spect

SUBMITTER: Kvasnicka A 

PROVIDER: S-EPMC11567051 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature