Acute Kidney Injury in Deceased Organ Donors: Risk Factors And Impacts on Transplantation Outcomes.

ABSTRACT:

Background

Acute kidney injury in deceased donors (D-AKI) is one of the common causes of donor kidney discard. The risk factors for D-AKI and its impact on kidney transplantation outcomes are not yet fully understood.

Methods

This single-center, retrospective cohort study included 388 donors referred between June 2021 and December 2022. D-AKI was defined and staged according to kidney disease: Improving global outcomes criteria, and donor clinical variables were analyzed to identify risk factors for D-AKI. Delayed graft function and estimated glomerular filtration rate (eGFR) at 6 mo were evaluated in 369 kidney grafts transplanted from donors with and without D-AKI.

Results

AKI was present in 171 deceased donors (44.1%), with 117 (30.2%) classified as AKI stage 1 and

SUBMITTER: Jakubov K 

PROVIDER: S-EPMC11567699 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature