Psychological outcomes of dementia risk estimation in MCI patients: Results from the PreDADQoL project.

ABSTRACT:

Introduction

Understanding the impact of biomarker-based dementia risk estimation in people with mild cognitive impairment (MCI) and their care partners is critical for patient care.

Methods

MCI patients and study partners were counseled on Alzheimer's disease (AD) biomarker and dementia risk was disclosed. Data on mood, quality of life (QoL), and satisfaction with life (SwL) were obtained 1 week and 3 months after disclosure.

Results

Seventy-five dyads were enrolled, and two-thirds of the patients opted for biomarker testing. None of the participants experienced clinically relevant depression or anxiety after disclosure. All dyads reported moderate to high QoL and SwL throughout the study. Patients reported more subthreshold depressive symptoms 1 week and lower QoL a

SUBMITTER: Rostamzadeh A 

PROVIDER: S-EPMC11567867 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature