Sleep characteristics and recurrence in platinum-sensitive ovarian cancer survivors: A prospective cohort study.

ABSTRACT:

Objective

To describe characteristics of sleep (quality, duration, efficiency, and insomnia) in a cohort of high-grade epithelial ovarian cancer (EOC) survivors who have completed and responded to first-line chemotherapy, and to explore their relationships with disease recurrence.

Methods

In this cohort of 97 women, sleep and other factors were assessed at baseline and 4 months later. The distribution of participants by categories of sleep characteristics were calculated. Hazard ratios (HRs) and 95 % confidence intervals (95 % CI) for the association between each sleep characteristic and recurrence were estimated using the Cox proportional hazards model, and adjusted for confounding using propensity scores. Associations were estimated for all women and among those defined as

SUBMITTER: Benoit M 

PROVIDER: S-EPMC11567917 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature