Evaluating transurethral resection of the prostate over twenty years: a systematic review and meta-analysis of randomized clinical trials.

ABSTRACT:

Purpose

The goal of this systematic review is to assess the temporal changes in outcomes and complications of transurethral resection of the prostate (TURP) from 2000 to 2022.

Methods

We conducted a systematic review and meta-analysis of 103 randomized clinical trials from PubMed on TURP, involving 8521 patients. Studies were grouped by years: 2000-2004, 2005-2009, 2010-2014, and 2015-2022. We assessed International Prostate Symptom Score (IPSS), Peak Flow (Qmax), Post-void residue of urine (PVR), and post-operative complications. Heterogeneity was ranked as low (I² < 25%), moderate (I² = 25-75%), or high (I² > 75%).

Results

TURP significantly improved IPSS, Qmax, and PVR, with the most recent studies showing superior results in IPSS a

SUBMITTER: Porto JG 

PROVIDER: S-EPMC11568034 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature