Plasma metabolomic characteristics of atrial fibrillation patients with spontaneous echo contrast.

ABSTRACT:

Background

The spontaneous echo contrast (SEC) in patients with atrial fibrillation (AF) indicates a prethrombic state that ultimately progresses into thrombus formation. A comprehensive understanding of specific plasma metabolomics characteristics may protect AF patients from thrombus, particularly in the early stage.

Objectives

Through the investigation of metabolic pathways, we endeavor to uncover the metabolomic characteristics associated with SEC states, and to examine the differential metabolites by which may exert their influence on thrombotic states.

Methods

Patients with AF were enrolled, and the participants were divided into three groups based on the results of the echocardiogram: non-SEC, low-SEC and high-SEC group. Samples were collected and subjected to

SUBMITTER: Shi B 

PROVIDER: S-EPMC11568604 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature