Physical and psychological aspects of multiple sclerosis: Revisiting the Multiple Sclerosis Impact Scale (MSIS-29).

ABSTRACT:

Background

The MSIS-29 measures the physical and psychological impact of MS.

Objective

The associations between MSIS-29 domains and demographic/clinical aspects were examined and trajectories analysed over time.

Methods

Data were collected in the Trajectories of Outcome in Neurological Conditions study for a diverse population of people with MS, with follow-up for up to 5 years. Following Rasch analysis, minimal important change (MIC) was computed for ensuing total, physical and psychological domains.

Results

Fit to the Rasch model using data from 5921 participants validated physical, psychological and total domains, and the conversion table transforms raw scores to interval-level metric equivalents. These domains showed significant differences across demograph

SUBMITTER: Young CA 

PROVIDER: S-EPMC11568641 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature