How feasible is nutrition intervention research in eating disorders? Lessons learnt from a pilot parallel randomised controlled trial of tyrosine supplementation in adolescents with anorexia nervosa.

ABSTRACT:

Objective

Eating disorders are complex illnesses with high morbidity and mortality. Yet, there is promising evidence to support the effects of nutrition on the brain and behaviour. One proposed example is the use of tyrosine as an adjunct treatment in anorexia nervosa (AN). However, recruitment and retention in eating disorder clinical trials has posed difficulties for researchers. The aim of this study was to pilot test a parallel randomised controlled trial (RCT) of tyrosine supplementation to explore the feasibility of recruitment and retention, intervention adherence and data collection methods from the perspective of participants and researchers.

Method

Feasibility was assessed using numbers participating, questionnaire completion in patients and parent/carers completin

SUBMITTER: Hart M 

PROVIDER: S-EPMC11568674 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature