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Effect of vitamin C injections on exercise muscular performance and biochemical parameters in <i>Trichinella spiralis</i>-infected mice.


ABSTRACT:

Background

Trichinella spiralis is a worldwide intestinal nematode that can parasitize the striated muscles of its hosts at the larval stage. This study aims to evaluate potential of vitamin C for treating trichinellosis-related pathological problems in the infected muscles of mice.

Materials and methods

Thirty CD1 male Albino mice were divided into three groups (10 mice per group). Negative and positive control groups (0.9% NaCl) and the infected vitamin C group (10 mg/kg body weight). Two weeks post-infection, each group was intraperitoneally injected daily for two weeks with Vitamin C or saline. The performance of the muscles was assessed both before and after the treatment. After dissection, constant parts of striated muscles were removed for further assays. The s

SUBMITTER: Rashed HAE 

PROVIDER: S-EPMC11568815 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature