Clot migration in patients treated with tenecteplase versus alteplase before mechanical thrombectomy.

ABSTRACT:

Introduction

This study aimed to describe and analyze the rate of clot migration of vessel thrombosis to distal segments in patients with acute ischemic stroke (AIS) who received intravenous thrombolysis (IVT) with tenecteplase (TNK) and alteplase (ALT) before mechanical thrombectomy (MT). In addition, we aimed to determine the relationship between thrombus migration and functional prognosis.

Methods

This study followed the STROBE reporting guidelines. We performed a retrospective analysis of a series of patients from November 2017 to April 2023 with an AIS with thrombosis on CT imaging, treated with IVT (TNK or ALT, split into two distinct groups) prior to mechanical thrombectomy.

Results

Two hundred and fifty-six patients with large vessel occlusion (LVO) were inclu

SUBMITTER: Garcia-Alcantara G 

PROVIDER: S-EPMC11569452 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature