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STRUBBELIG defines a receptor kinase-mediated signaling pathway regulating organ development in Arabidopsis.


ABSTRACT: An open question remains as to what coordinates cell behavior during organogenesis, permitting organs to reach their appropriate size and shape. The Arabidopsis gene STRUBBELIG (SUB) defines a receptor-mediated signaling pathway in plants. SUB encodes a putative leucine-rich repeat transmembrane receptor-like kinase. The mutant sub phenotype suggests that SUB affects the formation and shape of several organs by influencing cell morphogenesis, the orientation of the division plane, and cell proliferation. Mutational analysis suggests that the kinase domain is important for SUB function. Biochemical assays using bacterially expressed fusion proteins indicate that the SUB kinase domain lacks enzymatic phosphotransfer activity. Furthermore, transgenes encoding WT and different mutant variants

SUBMITTER: Chevalier D 

PROVIDER: S-EPMC1157047 | biostudies-literature | 2005 Jun

REPOSITORIES: biostudies-literature