An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score.

ABSTRACT: Heart failure with preserved ejection fraction (HFpEF) is under-recognized in clinical practice. Although a previously developed risk score, termed H₂FPEF, can be used to estimate HFpEF probability, this score requires imaging data, which is often unavailable. Here we sought to develop an HFpEF screening model that is based exclusively on clinical variables and that can guide the need for echocardiography and further testing. In a derivation cohort (n = 414, 249 women), a clinical model using age, body mass index and history of atrial fibrillation (termed the HFpEF-ABA score) showed good discrimination (area under the curve (AUC) = 0.839 (95% confidence interval (CI) = 0.800-0.877), P < 0.0001). The performance of the model was validated in an international, multicenter cohort (

SUBMITTER: Reddy YNV 

PROVIDER: S-EPMC11570987 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature