Implementation of a rule-based algorithm to find patients eligible for cancer clinical trials.

ABSTRACT:

Objective

To explore implementing regular expressions (RegEx) to streamline patient identification and classification for matching to clinical trials.

Materials and methods

To prepare approaches needed to match patients to relevant cancer clinical trials, we combined NCI's Clinical Trials Search API to extract high-level eligibility criteria, including cancer type, stage, receptor/biomarker status, with similar data of patients with appointments in the upcoming week. Using RegEx, we prospectively identified all patients with breast, liver, or lung cancers at treatment decision points at 2 Cancer Centers' and 2 community hospitals', classified their cancer type, stage, and receptor/biomarker status. We evaluated accuracy using RegEx against manual reviews.

Results

Algo

SUBMITTER: Bickell NA 

PROVIDER: S-EPMC11570988 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature