Effect of NR1D1 on the proliferation and differentiation of yak skeletal muscle satellite cells.

ABSTRACT: The severe conditions at high altitudes, where yaks inhabit, contribute to delayed muscular growth and compromised tenderness of their muscle tissue. Myosatellite cells are responsible for the growth and regeneration of skeletal muscle after birth and have the potential to proliferate and differentiate, its development is closely related to meat quality, and the nuclear receptor gene NR1D1 is involved in muscle formation and skeletal muscle regulation. Therefore, in order to understand the effect of NR1D1 on muscle satellite cells, we identified the mRNA expression levels of marker genes specifically expressed in muscle satellite cells at different stages to determine the type of cells isolated. Eventually, we successfully constructed a primary cell line of yak muscle satelli

SUBMITTER: Zhe Y 

PROVIDER: S-EPMC11571325 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature