Differences Between Glycated Hemoglobin and Glucose Management Indicator in Real-Time and Intermittent Scanning Continuous Glucose Monitoring in Adults With Type 1 Diabetes.

ABSTRACT:

Background

This study demonstrates the difference between glucose management indicator (GMI) and glycated hemoglobin (HbA_1c) according to sensor mean glucose and HbA_1c status using 2 continuous glucose monitoring (CGM) sensors in people with type 1 diabetes.

Methods

A total of 275 subjects (117 Dexcom G6 [G6] and 158 FreeStyle Libre 1 [FL]) with type 1 diabetes was included. The G6 and FL sensors were used, respectively, over 90 days to analyze 682 and 515 glycemic profiles that coincide with HbA_1c.

Results

The mean HbA_1c was 6.6% in Dexcom G6 and 7.2% in FL profiles. In G6 profiles, GMI was significantly higher than HbA_1c irrespective of mean glucose (all P < .001, mean difference: 0.58% ± 0.49%). The GMI

SUBMITTER: Yoo JH 

PROVIDER: S-EPMC11571357 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature