Muscular dystrophy patients show low exercise-induced blood flow in muscles with normal strength.

ABSTRACT:

Objective

Neuromuscular evaluation increasingly employs muscle ultrasonography to determine muscle thickness, mean grayscale echointensity, and visual semiquantitative echotexture attenuation. However, these measures provide low sensitivity for detection of mild muscle abnormality. Exercise-induced intramuscular blood flow is a physiologic phenomenon, which may be impaired in mildly affected muscles, particularly in dystrophinopathies, and may indicate functional muscle ischemia. We aimed to determine if muscle blood flow is reduced in patients with neuromuscular disorders and preserved muscle strength, and if it correlates with echointensity and digital echotexture measurements.

Methods

Peak exercise-induced blood flow, echointensity, and echotexture were quantified in the

SUBMITTER: Gera O 

PROVIDER: S-EPMC11572729 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature