Matched oligoclonal bands: Diagnostic utility and clinical characteristics.

ABSTRACT:

Objective

To describe patient clinical characteristics associated with matched oligoclonal bands (OCB).

Methods

A retrospective review at the University of Utah examined patients with matched OCB from 2015 to 2020. Clinical data, diagnosis, and outcomes were collected. Patients were classified with either multiple sclerosis (MS), other inflammatory neurologic disorder (other-IND), or noninflammatory neurologic disorder (NIND).

Results

Of 539 identified patients, 436 (53.4% female) were matched-only, while 103 (43.7% female) were matched + unique. Patients with matched-only bands were older (57.4 ± 16 vs. 52 ± 14.2, p < 0.001) and more likely to have a history of autoimmune disease (40.1% vs. 28.2%, p = 0.024) and/or cancer (28.7% vs. 16.5%, p = 0.012). Patients with m

SUBMITTER: Hoshina Y 

PROVIDER: S-EPMC11572730 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature