Malignant transformation and tumour recurrence in sacrococcygeal teratoma: a global, retrospective cohort study.

ABSTRACT:

Introduction

Sacrococcygeal teratoma (SCT) is a rare congenital tumour. The risk of malignancy and recurrence is not well defined. Previous studies are small and report differing conclusions about the timing of surgery and the duration of follow-up. The authors studied the risk of malignant transformation and SCT recurrence after surgery to address these gaps.

Methods

This was a global retrospective cohort study. Data of consecutive SCT patients was obtained from 145 institutes in 62 countries. Malignant transformation, defined as malignancy at initial resection, malignant recurrence or death due to malignancy, and its risk factors were analysed.

Results

Of the 3612 included patients, 3407 entered analysis. The risk of malignant transformation of the initial tumour wa

SUBMITTER: van Heurn LJ 

PROVIDER: S-EPMC11573091 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature