Absence of Kidney Tubular Injury in Patients With Acute Heart Failure With Acute Kidney Injury.

ABSTRACT:

Background

Worsening renal function (WRF) is common in hospitalized patients being treated for acute heart failure. However, discriminating clinically significant WRF remains challenging. In patients hospitalized with acute heart failure, we evaluated if blood and urine biomarkers of cardiac and kidney dysfunction were associated with adverse outcomes.

Methods

We identified 175 of 927 participants in the AKINESIS study (Acute Kidney Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure Study) who met criteria for stage 1 or 2 Kidney Disease: Improvement Global Outcomes acute kidney injury during the first 3 days of hospitalization. We measured 24 blood and urine biomarkers from specimens collected within 24 hours of meeting acute kidney injury cr

SUBMITTER: Duff S 

PROVIDER: S-EPMC11573103 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature