MALTectomy and psoriasis risk in women: A prospective study in the French E3N prospective cohort.

ABSTRACT:

Background and aim

The involvement of mucosa associated lymphoid tissues (MALT) in the development of an autoimmune response in the skin is unclear and unstudied. In this study we sought to assess the relationship between removal of MALT tissues (MALTectomy) and the risk of development of psoriasis (overall or moderate-to-severe).

Methods

We conducted a prospective observational study based on E3N, a French cohort composed of 98 995 women born between 1925 and 1950 and insured by the health insurance of the national education system (MGEN). The study population included the 90 119 women that completed the 1990 baseline questionnaire with available information on MALTectomy and a valid incident diagnostic date for psoriasis. During the 1990-2018 follow-up period 2 433 inciden

SUBMITTER: Conte M 

PROVIDER: S-EPMC11573222 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature