Microbubble Contrast Agents Improve Detection of Active Hemorrhage.

ABSTRACT: Assessment of trauma-induced hemorrhage with ultrasound is particularly challenging outside of the clinic, where its detection is crucial. The current clinical standard for hematoma detection - the focused assessment with sonography of trauma (FAST) exam - does not aim to detect ongoing blood loss, and thus is unable to detect injuries of increasing severity. To enhance detection of active bleeding, we propose the use of ultrasound contrast agents (UCAs), together with a novel flow phantom and contrast-sensitive processing techniques, to facilitate efficient, practical characterization of internal bleeding. Within a the custom phantom, UCAs and processing techniques enabled a significant enhancement of the hemorrhage visualization (mean increase in generalized contrast-to-noise ratio of 17

SUBMITTER: Schoen S 

PROVIDER: S-EPMC11573402 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature